Research Topics

Receptor pathology, metabolism and cellular kinetic study; environmental toxicology; gastrointestinal pharmacology; clinical pharmacology of active drugs on the central nervous system.
Antineoplastic drugs pharmacology; transplant pharmacology; pharmacoepidemiology and pharmacoeconomics of active drugs on the central nervous system, the cardiovascular system and gastrointestinal system.
Pharmacology and molecular mechanisms associated to neurodegenerative diseases; neuroinflammation in neurodegenerative diseases; single-cell -omics and nanotechnology for precision medicine applications in neurodegenerative diseases.
Environmental effects on the immune system; Pharmacology of the signaling transduction systems in the neurologic, oncologic and immune system diseases.
Neurobiology and Behavioural Pharmacology of Neurodevelopmental Disorders.

Projects

Characterization of extracellualr vescicles (EV) derived from astrocytes and glioma stem cells
Research group: Sergio Schinelli

Harnessing the heterogeneity of neuroinflammatory responses to tackle neurodegeneration in Amyotrophic Lateral Sclerosis
Research group: Marco Peviani

Modulation of cancer stem cell adhesion to human bone and endothelial cells by integrins antagonists in a 2D and 3D scaffold dynamic mode
Research group: Mayra Paolillo

Nature-inspired new hybrids to counteract oxidative stress and inflammation in aging and neurodegeneration
Research group: Cristina Lanni

Pharmacological and functional aspects of nutraceutical supplements: physiological mechanisms and impact on performance fatigability outcomes
Research group: Fausto Feletti

Pharmacological targets in gastrointestinal dysfunction
Research group: Pastoris Ornella

Role of the ERK signalling pathway in Neurodevelopmental Disorders: focus on murine and human models of 16p11.2 Copy Number Variations (CNVs)
Research group: Riccardo Brambilla

Searching for new molecules able to counteract diabetic retinopathy: HuR as a novel therapeutic target
Research group: Alessia Pascale

Study of molecular mechanisms and new pharmacological targets in age-related ocular diseases
Research group: Marialaura Amadio

The role of FXR receptor in the modulation of ADMA-mediated cardiovascular risk in metabolic syndrome
Research group: Mariapia Vairetti

The role of mGlu5 receptor in the modulation of liver injury in NAFLD/NASH
Research group: Andrea Ferrigno

Transcriptional modulation of the rack1 gene and RACK1 expression: role of steroid hormones and significance in health and aging
Research group: Marco Racchi