Research Topics

Receptor pathology, metabolism and cellular kinetic study; environmental toxicology; gastrointestinal pharmacology; clinical pharmacology of active drugs on the central nervous system.
Antineoplastic drugs pharmacology; transplant pharmacology; pharmacoepidemiology and pharmacoeconomics of active drugs on the central nervous system, the cardiovascular system and gastrointestinal system.
Pharmacology and molecular mechanisms associated to neurodegenerative diseases; neuroinflammation in neurodegenerative diseases; single-cell -omics and nanotechnology for precision medicine applications in neurodegenerative diseases.
Environmental effects on the immune system; Pharmacology of the signaling transduction systems in the neurologic, oncologic and immune system diseases.
Neurobiology and Behavioural Pharmacology of Neurodevelopmental Disorders.

Projects

Harnessing the heterogeneity of neuroinflammatory responses to tackle neurodegeneration in Amyotrophic Lateral Sclerosis
Research group: Marco Peviani

Targeting glioblastoma stem cells: the nicotinamide phosphoribosyltransferase (NAMPT) as a novel terapeutic target in glioblastoma
Research group: Mayra Paolillo

Gut-brain axis: misalignment in glymphatic system functionality as a driver of neurodegeneration in DSS-driven colitis model
Research group: Cristina Lanni

Patient-derived human cellular models to study neurodevelopmental disorders and to design novel therapeutic approaches
Research group: Riccardo Brambilla, Ilaria Maria Morella

Searching for new molecules able to counteract diabetic retinopathy
Research group: Alessia Pascale

Study of molecular mechanisms and new pharmacological targets in age-related ocular diseases
Research group: Marialaura Amadio

Pharmacological modulation of liver fat accumulation and fibrosis in obesity
Research group: Andrea Ferrigno

Transcriptional modulation of the rack1 gene and RACK1 expression: role of steroid hormones and significance in health and aging
Research group: Marco Racchi